비스포스포네이트 관련 악골괴사에 대한 연구: 증례보고 및 문헌문석
Study on bisphosphonate-related osteonecrosis of the jaw (BRONJ): case report and literature review
김여갑, 이백수, 권용대, 서준호, 진상미,
소속 상세정보
김여갑 ( Kim Yeo-Gap ) - 경희대학교 치의학전문대학원 구강악안면외과학교실
이백수 ( Lee Baek-Soo ) - 경희대학교 치과대학 구강악안면외과학교실
권용대 ( Kwon Yong-Dae ) - 경희대학교 치과대학 구강악안면외과학교실
서준호 ( Suh Joon-Ho ) - 경희대학교 치과대학 구강악안면외과
진상미 ( Jeen Sang-Mi ) - 경희대학교 치의학전문대학원
KMID : 0355620100360040291
Abstract
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of Bisphosphonates (BPs) use. These days, oral bisphosphonates are normally prescribed to treat osteoporosis. Intravenous BPs are used extensively to treat osteolytic bone lesions related to multiplemyeloma and bone metastasis of solid cancers, breast cancer or prostate cancer. As the prescription of BPs is universalized and the number of people treated with BPs is increasing, an accurate understanding and proper management of BRONJ are required. The aim of this study was to improve the linicians’understanding of BRONJ by reviewing the literature. To achieve this, this paper introduces case reports as well as the current concept of BRONJ based on the 2009 updates by American Association of Oral and Maxillofacial (AAOMS) including the definition, epidemiology, etiology, diagnosis, treatment and prevention of BRONJ.
키워드
Bisphosphonate; Osteonecrosis; Osteoporosis; Jaw diseases
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